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Home/Prof. Sezer Saglam, M.D.

Prof. Sezer Saglam, M.D.

DEPARTMENT : Medical Oncology

PRIMARY LOCATION : Gayrettepe Florence Nightingale Hospital

LANGUAGES : English, Turkish

  • Gastrointestinal Cancers  
  • Stomach Cancer  
  • Ewing Sarcoma  
  • Internal medicine
Medical Oncology Specialization Training
2005
Istanbul University Oncology Institute
1996
Istanbul University Cerrahpaşa Faculty of Medicine
Internal Medicine Specialization Training
1991
Ege University Faculty of Medicine

We are thrilled to announce that the Asia Research Awards in association with United Medical Council, Times of Research, Z24 News and the World Research Council nominated Prof. Dr. Sezer Sağlam to receive the International Best Researcher Award for his excellence in “The Prognostic Role of VEGFR-2 Gene Amplification in Relation to Serum AFP Levels Among Liver-Transplanted Patients with Hepatocellular Carcinoma” at the International Congress for Research Excellence on 26 January 2024 in Trichy, Tamil Nadu, India.

The Prognostic Role of VEGFR-2 Gene Amplification in Relation to Serum AFP Levels Among Liver-Transplanted Patients with Hepatocellular Carcinoma

A new approach for leptomeningeal metastases: chemotherapy administered through lumbar intrathecal port

1.Topuz E, Eralp Y, Saglam S, Saip P, Aydiner A, Berkman S, Yavuz E. “Efficacy of intraperitoneal cisplatin as consolidation  therapy in patients with pathologic complete remission following front-line therapy for epithelial ovarian cancer.  Consolidative intraperitoneal cisplatin in ovarian cancer.”Gynecol Oncol. 92(1): 147–5, 2004. 

2.Balci NC, Akun E, Erturk M, Saglam S, Inan N, Balci Y. “Renal-related perinephric fluid collections: MRI findings.” Magn  Resonance Imaging. 23(5): 679–84, 2005. 

3.Basaran M, Bavbek ES, Saglam S, Eralp L, Sakar B, Atalar AC, Bilgic B, Ozger H, Onat H. “A phase II study of cisplatin,  ifosfamide and epirubicin combination chemotherapy in adults with nonmetastatic and extremity osteosarcomas.”  Oncology. 72(3–4): 255–60, 2007. 

4.Sakar B, Gumus M, Basaran M, Argon A, Ustuner Z, Ustaoglu MA, Saglam S, Guney N, Tenekeci AN, Aykan NF. “XELOX  followed by XELIRI or the reverse sequence in advanced colorectal cancer.” Oncology. 73(5–6): 298–304, 2007. 

5.Topuz E, Derin D, Can G, Kürklü E, Cinar S, Aykan F, Cevikbaş A, Dışçi R, Durna Z, Sakar B, Saglam S, Tanyeri H, Deniz  G, Gürer U, Taş F, Güney N, Aydiner A. “Effect of oral administration of kefir on serum proinflammatory cytokines on  5-FU induced oral mucositis in patients with colorectal cancer.” Invest New Drugs. 26(6): 567–72, 2008. 

6.Balci NC, Befeler AS, Bieneman BK, Fattahi R, Saglam S, Havlioglu N. “Fat containing HCC: findings on CT and MRI  including serial contrast-enhanced imaging.” Acad Radiol. 16(8): 963–8, 2009. 

7.Balci NC, Perman WH, Saglam S, Akisik F, Fattahi R, Bilgin M. “Diffusion-weighted magnetic resonance imaging of the  pancreas.” Top Magn Reson Imaging. 20(1): 43–7, 2009. 

8.Saglam S, Suzme R, Gurdol F. “Serum tumor necrosis factor-alpha and interleukin-2 concentrations in newly diagnosed  ERBB2 (HER2/neu) positive breast cancer patients.” Int J Biol Markers. 24(3): 142–6, 2009. 

9. Saglam S, Aykan NF, Şakar B et al. A pilot study evaluating the safety and toxicity of epirubicin, cisplatin, and UFT (ECU  regimen) in advanced gastric carcinoma. Journal of Gastrointestinal Oncology.2; 219-26, 2011 

10.Effects of surgical laparoscopic experience on the short-term postoperative outcome of rectal cancer: results of a  high volume single center institution.Balik E, Asoglu O, Saglam S, Yamaner S, Akyuz A, Buyukuncu Y, Gulluoglu M,  Bulut T , Bugra D. Surg Laparosc Endosc Percutan Tech. 2010;20:93-9. 

11.Can diffusion-weighted MRI determine complete responders after neoadjuvant chemoradiation for locally advanced  rectal cancer?Engin G, Sharifov R, Güral Z, Sağam EK, Sağlam S, Balik E, Asoğu O, Yamaner S, Güllüoğu M, Kapran Y,  Özel S.Diagn Interv Radiol. 2012;18:574-81. 

12.Modified DCF (mDCF) regimen seems to be as effective as original DCF in advanced gastric cancer (AGC). Keskin S,  Yıldız I, Sen F, Aydogan F, Kilic L, Ekenel M, Saglam S, Sakar B, Disci R , Aykan F.Clin Transl Oncol. 2012  

13.Saglam S, Bugra D, Kaytan Saglam E, Yamaner S, Asoglu O, Balik E, Oral EN, Sakar B, Kizir A, Kapran Y, Camlıca H.  “Prospective randomized study comparing fourth-week surgery versus eighth-week surgery after neoadjuvant  concomitant radiotherapy and infusional 5-FU in T3-4/N0+ rectal cancer: Istanbul R-01 Study”. J Clin Oncol 27:15s,  (suppl; abstr 4131), 2009 

14.Saglam S, Arifoglu A, Saglam EK, Asoglu O, Yamaner S. “Induction chemotherapy plus concurrent chemoradiotherapy  (HART) sor squamous cell carcinoma of the esophagus: Preliminary analysis of the phase II trial”. Proc. ASCO GI  Annual Meeting of the American Society of Clinical Oncology, Gastrointesitinal Cancer, USA, abstr no: 75, 2008. 

15.Sakar B, Gumus M, Argon A, Guney N, Saglam S, Basaran M, Ustaoglu MA, Ustuner Z, Aykan F. “XELOX followed  by XELIRI or the reverse sequence in advanced colorectal cancer”. Proc. ASCO GI Annual Meeting of the American  Society of Clinical Oncology, Gastrointesitinal Cancer, USA, abstr no: 307, 2007 

16.Saglam S. “Epirubicine, cisplatin, UFT (ECU Regimen) in advanced gastric carcinoma”. Proc. ASCO GI Annual Meeting  of the American Society of Clinical Oncology, Gastrointesitinal Cancer, USA, abstr no:86, 2006. 

17.Balik E, Bektas H, Yamaner S, Bugra D, Bulut T, Saglam S, Saglam E, Akyuz A, Buyukuncu A, Sokucu N. “The effects  of neoadjuvant chemo-radiotherapy on the complication rates in rectal cancer surgery”. XXI. Biennial Congress of  International Society of The University of Colon and Rectal Surgeons 25-28 June, USA, Abstr no: 93, 2006 

18.Balik E, Bektas H, Keskin M, Bugra D, Yamaner S, Bulut T, Saglam S, Saglam E, Sokucu N, Buyukuncu Y, Akyuz A.  “Surgical timing for rectal cancer operation after neoadjuvant radiotherapy and chemotherapy”. XXI. Biennial  Congress of International Society of The University of Colon and Rectal Surgeons 25-28 June, USA, Abstr no: 95, 2006 

19.Bitisik O, Saip P, Saglam S, Dalay N. “Detection of circulating breast cancer cells in relation to therapy” Journal of  Clinical Oncology, ASCO Annual Meeting Proceedings. Vol 23, No. 16S, Part I of II (June 1 Supp. abstr no:689), 2005. 

20.Sakar B, Aykan NF, Saglam S, Ustuner Z. “Long-term survival after curative resection for pancreatic ductal  adenocarcinoma” Journal of Clinical Oncology, ASCO Annual Meeting Proceedings (Post-Meeting Edition). Vol 22, No  14S (July 15 Supp. Abstract no: 4227), 2004.  

21. Saglam S. “Monoclonal Antibodies that Block Signaling [cd 20 (rituximab), Her 1 Blockers (cetuximab, Panitumumab,  Matuzumab, Nimotuzumab), Her 2 Blockers (trastuzumab), Her-1-2 Blocker (pertuzumab), Igr-1r, Vegf (  bevacizumab), Vegf Trap, Vegfr1, Vegfr2, Trail R1 (mapatumumab), Trail R2 (lexatumumab), Pdgf-alpha Integrins]”.  Turkish Clinics Journal/Medical Oncology – New Drug Therapies in Oncology Special Issue; Volume/Volume: 2 (1), 37- 44, 2009. 

22.Sağlam S, AYKAN NF “Treatment of Neuroendocrine Tumors” Review. Dialogue in Endocrinology; vol: 2, 142- 6, 2007. 

23.Uçar A, Yekeler E, Yıldırım Dönmez F, Tunacı M, Sağlam S, Acunaş G. “Uterus Lyomyosarcoma with Sternal Metastasis”  Istanbul Faculty of Medicine Journal; Volume: 68 (3), 078-080, 2005. 

24.Kuter S, Sağlam S. “Blood and blood components used to prevent transfusion-induced graft-versus-host disease,  physical structure of irradiation devices, radiation doses, dosimetric measurements, irradiation doses and clinical  indications”. Turkish Journal of Oncology, Volume: 24 (3), 2009  

25.Sağlam S, AYKAN NF “Treatment of Neuroendocrine Tumors” Review. Dialogue in Endocrinology; vol: 2, 142- 6, 2007.

26.Uçar A, Yekeler E, Yıldırım Dönmez F, Tunacı M, Sağlam S, Acunaş G. “Uterus Lyomyosarcoma with Sternal Metastasis”  Istanbul Faculty of Medicine Journal; Volume: 68 (3), 078-080, 2005. 

27.Kuter S, Sağlam S. “Blood and blood components used to prevent transfusion-induced graft-versus-host disease,  physical structure of irradiation devices, radiation doses, dosimetric measurements, irradiation doses and clinical  indications”. Turkish Journal of Oncology, Volume: 24 (3), 2009 Presented at National Scientific Meetings and  Papers Printed in Proceedings Books 1. Topuz E, Eralp Y, Sağlam S, Saip P, Aydıner A, Berkman S, Yavuz E, “Efficacy of  intraperitoneal cisplatin treatment as consolidation therapy in patients with ovarian cancer who achieved complete  remission after primary chemotherapy”, 15. National Cancer Congress, P 310, Antalya, 2003. 

28.Balık E, Keskin M, Bektaş H, Sağlam S, Sağlam E, Buğra D, Yamaner S, Bulut T, Sökücü N, Büyükuncu Y, Akyüz A.  “Comparison of early and late term complications of rectal cancer patients who underwent surgery at the 4th and  8th weeks after neoadjuvant chemoradiotherapy”. National Surgery Congress, 24-28 May, Antalya, 2006 

29.Balık E, Keskin M, Bektaş H, Sağlam S, Sağlam E, Yamaner S, Buğra D, Bulut T, Büyükuncu Y, Sökücü N, Akyüz A.  “The effect of neoadjuvant chemoradiotherapy on perioperative and early complications in rectal cancer”. National  Surgery Congress, 24-28 May, Antalya, 2006. 

30.Sağlam S, Başaran M, Onat H, Bavbek S. “The effect of gastrectomy on survival in patients with primary gastric  lymphoma”. 1st Medical Oncology Congress, 29 March – 2 April, Antalya, abstr no: 213, 2006. 

31.Saglam S, Aykan F, Şakar B, Author A. “Epirubicine, cisplatin, UFT (ECU Regimen) in advanced gastric cancer” 1st  Medical Oncology Congress, 29 March – 2 April, oral presentation 5, Antalya, 2006. 

32.Ergen A, Sağlam S, Almaç Z, Tuncer S, Peksayar G. “Carcinoid tumor and orbital metastasis: Case report” XII. National  Cancer Congress, P 629, Antalya, 2007. 

33.Vural S, Karadağ Ç. A. Tanık C, Sağlam S, Karaman S, Urgancı N, Erdem E.” “Childhood colon adenocarcinoma with  epididymal metastasis: Case report” XIII. National Cancer Congress, P 330, Antalya, 2009. 

34.Balık E, Keskin M, Bektaş H, Sağlam S, Sağlam E, Buğra D, Yamaner S, Bulut T, Sökücü N, Büyükuncu Y, Akyüz A.  “Comparison of early and late term complications of rectal cancer patients who underwent surgery at the 4th and  8th weeks after neoadjuvant chemoradiotherapy”. National Surgery Congress, 24-28 May, Antalya, 2006 

35.Balık E, Keskin M, Bektaş H, Sağlam S, Sağlam E, Yamaner S, Buğra D, Bulut T, Büyükuncu Y, Sökücü N, Akyüz A.  “The effect of neoadjuvant chemoradiotherapy on perioperative and early complications in rectal cancer”. National  Surgery Congress, 24-28 May, Antalya, 2006. 

36.Sağlam S, Başaran M, Onat H, Bavbek S. “The effect of gastrectomy on survival in patients with primary gastric  lymphoma”. 1st Medical Oncology Congress, 29 March – 2 April, Antalya, abstr no: 213, 2006. 

37.Saglam S, Aykan F, Şakar B, Author A. “Epirubicine, cisplatin, UFT (ECU Regimen) in advanced gastric cancer” 1st  Medical Oncology Congress, 29 March – 2 April, oral presentation 5, Antalya, 2006. 

38.Ergen A, Sağlam S, Almaç Z, Tuncer S, Peksayar G. “Carcinoid tumor and orbital metastasis: Case report” XII. National  Cancer Congress, P 629, Antalya, 2007. 

39.Vural S, Karadağ Ç. A. Tanık C, Sağlam S, Karaman S, Urgancı N, Erdem E.” “Childhood colon adenocarcinoma with  epididymal metastasis: Case report” XIII. National Cancer Congress, P 330, Antalya, 2009.