The Bone Marrow Transplant (BMT) Center at Group Florence Nightingale Hospitals stands among Europe’s and Turkey’s leading destinations for bone marrow transplantation. Our center performs a consistently high volume of 100+ transplants annually, delivering exceptional outcomes grounded in science, compassion, and the highest international standards. Guided by a mission to deliver hope and comprehensive advanced …
Advanced Care at the Bone Marrow Transplant Center
The Bone Marrow Transplant (BMT) Center at Group Florence Nightingale Hospitals stands among Europe’s and Turkey’s leading destinations for bone marrow transplantation. Our center performs a consistently high volume of 100+ transplants annually, delivering exceptional outcomes grounded in science, compassion, and the highest international standards. Guided by a mission to deliver hope and comprehensive advanced care, we accompany our patients through every stage of their bone marrow transplant journey.
Since 2008, we have successfully completed more than 1500 transplants, reflecting both our extensive experience and the trust patients place in our team.
Our program proudly holds Joint Accreditation Committee-ISCT & EBMT (JACIE) accreditation, the highest global standard in stem cell transplantation. This accreditation recognizes excellence in clinical outcomes, laboratory processes, and multidisciplinary teamwork. At every stage of care, expert hematologists, oncologists, nurses, psychologists, dietitians, and transplant coordinators work together to support patients and their families.
Comprehensive Expertise and Proven Results
Our center offers the full spectrum of modern transplant modalities, allowing us to tailor treatment to each patient’s clinical and personal needs:
- Autologous Transplant: Using the patient’s own stem cells, collected during remission and prepared using advanced laboratory methods.
- Allogeneic Transplant: Stem cells from a fully matched related or unrelated donor.
- Haploidentical Transplant: A half-matched donor—often a parent, child, or sibling—expanding access to transplantation for patients without a fully matched donor.
Leveraging our extensive experience of over 1,500 transplants and strict evidence-based protocols, our first-year survival outcomes consistently meet or exceed international benchmarks. Furthermore, our lifelong follow-up programs are designed to monitor long-term recovery, strengthen the immune system, and effectively manage any late complications.
Our specialists not only contribute to scientific progress through regular publications, clinical research, and active participation in international conferences, but also fulfill our mission by training future hematologists through structured educational programs.
What Is Bone Marrow?
Bone marrow is the soft, sponge-like tissue inside the bones that acts as the body’s stem cell factory. It produces:
- Red blood cells, which carry oxygen
- White blood cells, which fight infections and strengthen the immune system
- Platelets, which control bleeding
Stem cells are the “parent” cells that create all blood cell types. Healthy bone marrow is essential for immunity, oxygen delivery, and healing.
Bone Marrow Transplant Procedure
A bone marrow transplant—also called a stem cell transplant—replaces damaged or diseased bone marrow with healthy stem cells. It is a complex, highly coordinated process that includes the following stages:
1. Examination and Pre-Transplant Assessment
A full evaluation of the patient’s condition, including laboratory tests, imaging, organ function assessments, and discussions with the transplant team.
2. Stem Cell Collection (Harvesting)
Stem cells are collected from the patient (autologous) or donor (allogeneic or haploidentical) through:
- Apheresis, a blood-filtering machine
- Or, in selected cases, direct bone marrow aspiration
3. Conditioning Treatment
High-dose chemotherapy, sometimes combined with radiotherapy, prepares the body to receive new stem cells by removing diseased cells and suppressing the immune system.
4. Transplantation (Stem Cell Infusion)
The healthy stem cells are infused into a vein—similar to receiving a blood transfusion. The infusion itself is painless.
5. Recovery and Engraftment
Patients stay in specially designed rooms to protect them during the period of low immunity (neutropenia). The focus is on:
- Preventing infections
- Managing side effects
- Supporting nutrition
- Monitoring for complications such as graft-versus-host disease (GVHD)
Within 2–4 weeks, the new stem cells begin producing healthy blood cells—a process called engraftment.
Why Is a Bone Marrow Transplant Necessary?
A stem cell transplant is often the only curative treatment for serious conditions, including:
- Leukemia A cancer of the blood and bone marrow. It causes the bone marrow to make too many abnormal white blood cells, which crowd out the healthy blood cells needed to fight infection, stop bleeding, and carry oxygen.
- Non-Hodgkin’s Lymphoma (NHL) A cancer that begins in the lymphatic system (the disease-fighting network). It causes a type of white blood cell called a lymphocyte to grow out of control, forming tumors and weakening the immune system.
- Hodgkin Lymphoma (HL) A cancer similar to NHL, also starting in the lymphatic system. It is distinguished by the presence of a specific, abnormal cell called the Reed-Sternberg cell.
- Multiple Myeloma A cancer of the plasma cells (a type of white blood cell) found in the bone marrow. These cancerous cells build up, damaging the bone and interfering with the production of healthy blood cells.
- Severe Aplastic Anemia A serious condition where the bone marrow is damaged and stops producing enough new blood cells (red, white, and platelets). This leads to fatigue, higher risk of infection, and uncontrolled bleeding.
- Thalassemia and Sickle Cell Disease Inherited blood disorders where the body produces abnormal hemoglobin, the protein in red blood cells that carries oxygen. This causes red blood cells to be fragile (Thalassemia) or sickle-shaped (Sickle Cell), leading to severe anemia and organ damage.
- Other Inherited Immune and Blood Disorders A wide group of diseases passed down through families, where the bone marrow fails to make healthy white blood cells (leading to poor immunity) or other necessary blood components.
Without treatment, these conditions may cause life-threatening infections, organ failure, or severe bleeding.
Who Is Eligible for a Bone Marrow Transplant?
Eligibility is determined through a multidisciplinary team assessment. Key factors include:
- Overall health and organ function
- Disease type and stage
- Response to previous treatments
- Availability of a suitable donor (for allogeneic/haploidentical transplant)
- A personalized risk–benefit evaluation
Bone Marrow Transplant Cost
The cost of a transplant varies depending on:
- Type of transplant (autologous is typically lower cost)
- Hospital stay duration
- Medication requirements
- Donor-related procedures
- Management of complications
Our International Patient Services team offers transparent cost estimates, package options, and guidance throughout the financial planning process.
Bone Marrow Transplant Success Rate
Our center maintains high survival and engraftment outcomes, supported by:
- Experienced transplant teams
- Advanced infection control measures
- Individualized conditioning protocols
- Dedicated follow-up programs
- Continuous monitoring for GVHD and other complications
Long-term success depends not only on the transplant but also on personalized care during recovery and beyond.
Contact Us for Expert Care
We welcome patients from all over the world and provide full support throughout the transplant journey.
To request a personalized treatment plan or speak with our transplant team:
- Phone: +44 207 637 77 89
- WhatsApp: +90 549 712 60 60
- Email: apply@florencehealthcare.international
Our team is here to help you every step of the way.
Frequently Asked Questions
What is a bone marrow transplant?
A procedure that replaces damaged bone marrow with healthy stem cells to treat leukemia, lymphoma, and other serious blood disorders.
Why choose a JACIE-accredited center?
JACIE accreditation ensures excellence in clinical quality, patient safety, laboratory standards, and transplant expertise.
Is the transplant painful?
The stem cell infusion is painless. Side effects may occur during conditioning, but they are managed with comprehensive supportive care.
Can I use my own stem cells?
Yes—this is called an autologous transplant.
How do I know if I’m eligible?
Eligibility is determined by a multidisciplinary medical evaluation based on your health status, disease type, and donor availability.
